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39 In addition, the Inclusion complex of zerumbone isolated from Zingiber zerumbet (L)

Subsequently, mevalonate is modified to produce isopentenyl pyrophosphate (IPP), which is finally converted to the direct precursors of cholesterol, squalene, and lanosterol ( de novo synthesis, as it is not permeable to circulating lipoprotein-bound cholesterol ( Once available, cholesterol is transported to mitochondria by proteins such as the 18 kDa translocator protein (TSPO) and the steroidogenic acute regulatory protein (StAR) ( Regarding the local synthesis of P4, the human CNS produces this hormone from prenatal stages through postnatal life

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Acesta este implicat n meninerea echilibrului antioxidant, n protecia celulelor mpotriva stresului oxidativ i n susinerea proceselor naturale de detoxifiere, n special la nivel hepatic