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Acetonitrile, hexane, dichloromethane, and ethyl acetate are routinely used organic solvents (Joshi and Adhikari, 2019)

Whereas EL is still working after heating to 100C at acidic and neutral pH, its activity is markedly affected by alkaline pH [65]

217 In another study, the deubiquitinating enzyme OTUD1 inhibited the NF-B pathway by interacting with RIPK1 and inhibited the excessive production of the proinflammatory cytokines TNF-, IL-6, and IL-1 in UC, thereby inhibiting colon inflammation

Within the cells, choline is phosphorylated into phosphocholine or oxidized into betaine

10.1136/ard-2023-225041 169 MurrayR.WinklerP