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The drugs were used at their IC50 concentrations to maximize synergy and induce a high rate of cell death

It moves the discussion beyond hype and gives patients a practical distinction they can actually use when thinking about the next step in their weight-loss journey

Those most vulnerable to B12 deficiencies include vegans, older adults, individuals with gastrointestinal absorption problems, and those whove had weight-loss surgery

It is contraindicated in certain conditions such as active malignancy and must be used cautiously in those with diabetes, prediabetes, or a history of pituitary disease, which is why careful screening and regular monitoring are essential