[DOI] [PubMed] [Google Scholar] 190.Machado M.L., Arantes L.P., da Silveira T.L., Zamberlan D.C., Cordeiro L.M., Obetine F.B.B., da Silva A.F., da Cruz I.B.M., Soares F.A.A., Riva de Oliveria P
Long-term modeling is constrained by short peptide half-life, adaptive receptor responses, and the logistical complexity of maintaining controlled pulsatile exposure
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MATERIALS AND METHODS: We measured the expression of ghrelin and growth hormone secretagogue receptor 1a (GHS-R1a) in rat osteoblasts using RT-PCR and immunohistochemistry (IHC)
In summary, although IBD is a multifactorial disease in which activation of inflammatory cells is thought to play a key role for its development, the synergism between ROS generation and subsequent GSH depletion induced by TNBS appears to be a key event, at least in this model of acute colitis induced by TNBS+ethanol
