Mouse embryos cultured in PF or FF from endometriosis patients show decreased cell number and rates of growth, decreased cleavage and blastulation rates, and increased rates of DNA fragmentation, developmental arrest, embryo toxicity, and apoptosis than mouse embryos cultured in PF or FF from control patients (109, 110, 135141)
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Targeted acquisition of MS/MS spectra was performed in the parallel reaction monitoring mode, using the Xcalibur software 2.2
Our sample size exceeds 420,000, enabling us to better determine the genome-wide risk and outcome of causation