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Similarly, in another animal study, grain-fed rats exhibited hyperglycemia due to de novo lipogenesis, which led to abnormal lipids and contributed to inflammation and impaired neuronal function ( Figure 4 Figure 5 Notably, the consumption of UPF can adversely affect the permeability of important lipid membranes, including the BBB (88)

Results showed that a twice daily IGF-1 dose of 120mcg/kg produced almost identical effects as that of a twice daily 80mcg/kg dose [18]

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Figure 3E, middle)