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Modern life in this city long working weeks, year-round sun exposure, frequent travel, intense training, sleep disruption and chronic background stress generates a sustained load of oxidative stress that the body's antioxidant systems were never designed to manage on their own

The reactive arm identifies proteins that escape productive folding or become damaged over time and routes them into clearance or repair pathways, primarily the ubiquitinproteasome system and lysosomal autophagy (Fig

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It also has been shown to improve athletic performance and recovery in healthy, physically active people, whether theyre serious competitive athletes or weekend warriors

O'Reilly for giving me invaluable context on this fascinating area of research