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For example, GLP-1s are drugs that take an existing class of short-lived peptides and modify them to extend their activity duration, which turns them into drugs, following rigorous clinical testing

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E Cd /C cr producing a 10% reduction in eGFR Given that eGFR is a clinically relevant parameter and a diagnostic criterion of CKD, the results discussed above indicate the potential utility of eGFR in defining Cd exposure limits

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