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Patients must strictly follow the doctor's instructions, not self-adjust the dosage, and should not stop the medication without the doctor's approval 5

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- People with significant liver disease (the 9-month monkey toxicology study showed dose-dependent periportal vacuolation in hepatocytes that the FDA flagged as a possible safety signal)

This includes a comprehensive review of your medical history, current medications, allergies, and any underlying health conditions that may impact your treatment