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If the research context also involves chronic inflammation, gut-related models, or autoimmune-style settings, KPV is what KLOW adds

Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)

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