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Previous reports demonstrated that HMGB1 interacted with CRM1 for active export from nuclear (7D), whereas, overexpression of GSTP substantially attenuated interaction between HMGB1 and CRM1

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Its broad cellular role makes it one of the most widely studied compounds in longevity, dermatology, and metabolic health research

In transdermal experiments, the system exhibited superior retention capacity and fluorescence visualization properties compared to conventional liposome or hydrogel-based delivery platforms