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By converting lipid peroxides (L-OOH) into non-toxic lipids, GPX4 counteracts oxygen- and iron-dependent lipid peroxidation, with GSH acting as a crucial cofactor

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Cytokines may be a pathway through which periodontitis causes kidney disease

Still, many patients flocked to these, despite the safety concerns and warnings from regulators about the risks

Some TFs induce DNA demethylation, such as nuclear factor-kappa B (Lichtenstein et al., 1994), Egr1/NGFI-A/Zif268/Krox-24 (Weaver et al., 2007), and the estrogen receptor that co-immunoprecipitates in the complex with DNMTs and the BER machinery (Metivier et al., 2008)