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Clarifying the core mechanisms and key influencing factors of the contradictory conclusions on the regulatory effects of mitophagy is not only of great significance for in-depth understanding of the role of mitophagy in the occurrence and development of related diseases, but also provides important theoretical support for subsequent disease prevention and treatment strategies targeting mitophagy

Nutrient deficient diets and high stress sedentary lifestyles contribute to this depletion

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Endocrinology 151 , 143152 (2010)

Administration of MSCs, G-CSF or Dihexa in our study did not mitigate the muscular atrophy in our SNR model similar to Song and co-workers [66] study in a rat hind-limb transplant model