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Abbreviations CVD: Cardiovascular disease ROS: Reactive oxygen species PUFAs: Polyunsaturated fatty acids GPX4: Glutathione peroxidase 4 AS: Atherosclerosis ACSL4: Long-chain-fatty-acid-CoA ligase 4 LPCAT3: Lysophosphatidylcholine acyltransferase 3 AdA: Adrenic acid MUFAs: Monounsaturated fatty acyl tails NCOA4: Nuclear Receptor Coactivator 4 SLC7A11: Solute carrier family 7 member 11 GSH: Glutathione FSP1: Ferroptosis suppressor 1 NOS2: Nitric oxide synthase 2 HSCs: Hematopoietic stem cells MI: Myocardial infarction HIF-1: Hypoxia-inducible factor-1 NRF2: Nuclear factor erythroid 2-related factor 2 AF: Atrial fibrillation HF: Heart failure VTE: Venous thromboembolism COVID-19: Coronavirus disease 2019 SARS-CoV-2: Severe acute respiratory syndrome coronavirus type 2 HO-1: Haem oxygenase-1 YAP1: Yes-associated protein 1 STAT3: Signal transducer and activator of transcription 3 IRF3: Interferon regulatory factor 3 SFXN1: Sideroflexin 1 References Yarovinsky TO, Su M, Chen C, Xiang Y, Tang WH, Hwa J

Vitamin C typically shows visible improvements in skin brightness and tone within 4-12 weeks of consistent daily application

Research into these natural antioxidants offers promising avenues for preventive and therapeutic strategies against oxidative stress-related diseases [18]

Clin Sci (Lond) 133:905917

Integrins are transmembrane receptors on leukocyte surfaces, consisting of and subunits