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Results of a Phase IIA Study

Increased HGF expression has been correlated to anoikis resistance by fibronectin signaling in HNSCC by disrupting the integrin signaling [90]

The parent BPC protein was first isolated and characterized in the early 1990s by Predrag Sikiric and colleagues at the University of Zagreb

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The N-terminal fragments formed by cleavage participate in pore formation in the cell membrane, ultimately leading to pyroptotic cell death