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Simultaneously, ROS disrupts insulin signaling in peripheral tissues by promoting IRS-1 serine phosphorylation and degrading phosphatidylinositol-3-kinase (PI3K)/Akt activation, leading to insulin resistance (Papaetis et al., 2025)

In vitro expression of a mouse tissue specific glutathione-peroxidase-like protein lacking the selenocysteine can protect stably transfected mammalian cells against oxidative damage

The stirring continued for another 12 h at room temperature, after which the mixture was transferred into 10 mL of deionized water while being sonicated

Metformin potentiates nephrotoxicity by promoting NETosis in response to renal ferroptosis

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