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Sleep Med Rev 44:8384 Cowen PJ, Parry-Billings M, Newsholme EA (1989) Decreased plasma tryptophan levels in major depression

It is naturally produced in the body, but its level gets depleted with age and environmental stressors

Thats not the same as FDA approval , but it would mean that pharmacies could compound them with a doctors prescription

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Power Dynamics in Urban Policy Formation Who are the middling actors, what are their positionalities, and how do they negotiate power within multi-level urban governance