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Summary: Vitamin B12 treatment typically begins producing early haematological responses within 34 days, with neurological symptoms starting to improve within 12 weeks, though complete symptom resolution may require several weeks to months depending on deficiency severity and treatment route

Simply injecting B12 won't lead to dramatic weight reduction

11,12 Methemoglobinemia classically presents with cyanosis, or bluish discoloration of the skin, particularly in the lips and nail beds

Sorescu D, Weiss D, Lassegue B, Clempus RE, Szocs K, Sorescu GP, Valppu L, Quinn MT, Lambeth JD, Vega JD, Taylor WR, Griendling KK

The possible application of ketamine in the treatment of depression in Alzheimers disease