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The Soxhlet method was observed to achieve a significantly higher curcumin yield (6.9%) compared to enzyme-assisted (4.1%), ultrasound-assisted (3.92%), and microwave-assisted (3.72%) methods (55)

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Clinical Status Human RCT | Observational | Animal | In vitro Primarily studied in preclinical and exploratory neurophysiological research contexts, with limited controlled human trials