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If that fails, consult solubility guidelines: try mild acid or base for charged peptides, or a bit of DMSO for very non-polar peptides4

106 In the destabilization of the medial meniscus (DMM) rat model, Overexpression of MFN2 in articular cartilage accelerated the progression of OA, while knockdown of MFN2 mitigated cartilage degeneration

MCT1 as a Drug Target An experimental drug from AstraZeneca, called AZD3965, blocks the activity of MCT1 and is already being clinically tested as a cancer treatment

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