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16 On the other hand, the investigational use of GIPR agonists (GIPRAs) has not yielded similar advantages, partly because of a lack of understanding of GIP dose-response actions

Of note, treatment with a supra-nutritional level of MK4 extended the survival time of Alb-creER T2 ;Gpx4 fl/fl mice under vitamin E-deficient conditions and robustly protected against related pathologic changes and lipid peroxidation in the liver (Fig