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OBrien JT, Ames D, Schweitzer I et al (1996) Enhanced adrenal sensitivity to adrenocorticotrophic hormone (ACTH) is evidence of HPA axis hyperactivity in Alzheimers disease

Results: Both treatments produced significant improvements from baseline in neuropathy on electromyography at day 60, and greater mean improvements were observed with thioctic acid (0.19 0.29 vs baseline) than with ALC (0.09 0.40 vs baseline), although the between-group difference was not statistically significant

The protocol is sustainable for years with appropriate monitoring and cycling

J Biotechnol 163:339345