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For non-enzymatic antioxidants, probiotics secreting EPS and antioxidant peptides (e.g., glutathione) can reduce oxidative damage and thus can prevent aging and various chronic diseases (Zhang et al., 2022

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Thus, by promoting intimal hyperplasia, these vascular disorders (which are related to smooth muscle cell proliferation, collagen accumulation, and the extracellular matrix modification that may result from homocysteinylation of the vascular wall structure leading to connective tissue deterioration) might contribute to the atherogenic tendency of hyperhomocysteinemia

Improved compliance: For some people, taking supplements with meals is easier to remember and stick to as a routine

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