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Nevertheless, pathways implicated in preclinical studies, including angiogenesis, inflammatory modulation, and collagen remodeling, intersect with biologic systems central to incision healing and complication avoidance, although these mechanistic signals have not been shown to translate into improved clinical outcomes

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To determine whether these BAL fluid levels were a reflection of intracellular GSH metabolism, freshly brushed and isolated HAECs were analyzed and compared to BAL fluid levels (Figure 1B)