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Currently, only one highly conceptual, fictionalized Phase 1/2 study (NCT07487363) exists in trial registries as a placeholder example for evaluating TB-500 in patients with stable atherosclerotic cardiovascular disease, further highlighting the absolute lack of real-world human data for the fragment

DNA repair (PARPs) PARP enzymes consume NAD+ to repair damaged DNA strands

Full details are provided in the Statistical Analysis Plan

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