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Its worth noting that this is a regulatory review process

In breast cancer, higher FERscore levels were positively associated with traits such as mesenchymal phenotype, stemness, immune cell infiltration, and cancer-associated fibroblast (CAF) enrichment, while they were negatively associated with features like estrogen response and DNA repair capacity (Hu et al., 2024)

SS-31 (Elamipretide)# Evidence Level: Phase 2/3 clinical trials | FDA Status: Investigational SS-31 concentrates 1,000-5,000 fold in the inner mitochondrial membrane, where it improves ADP sensitivity through the adenine nucleotide translocator (ANT) and reduces oxidative stress

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