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[59] The protocol included intravenous and oral administration, and is described in detail elsewhere

IV NAD therapy bypasses digestion and delivers this essential molecule directly into the bloodstreamallowing for rapid replenishment and systemic benefits

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10.1038/s44220-023-00145-6 232 KelmendiB.AdamsT

Depletion of tryptophan (a Candida metabolic substrate) reduces serotonin synthesis, while chronic gut inflammation elevates inflammatory cytokines (IL-6, TNF-) that independently suppress mood via neuroinflammatory pathways