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The calibration and validation results show that both in the control and the rd1 case, the model produces output for [GSH] and [GSSG] approximating trends in the experimental data, and there is notable uncertainty in the estimated parameters
We found that the ebselen could significantly promote SGN survival, decrease SGN apoptosis, and reduce intracellular ROS levels after peroxynitrite exposure in vitro , while the deficiency of GPX1 led to opposite patterns of the above effects
