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Subsequent examination of membranous GLUT1 expression in both tissues revealed that TXNIP overexpression led to a significant decrease of GLUT1 expression in the ileum and colon after metformin treatment, where metformin increased GLUT1 expression (Fig

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These include mild redness and swelling that resolves within hours, occasional bruising (typical of any subcutaneous injection), and mild burning or cramping reported by some users