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Gastrointestinal issues : Conditions like celiac disease or Crohn's disease can impair B12 absorption in the gut

Not only does improving sleep improve GI function, but improving GI health also improves sleep.[60] A poor sleep-wake cycle triggers inflammatory cytokines that can exacerbate inflammatory bowel disease (IBD) and disrupt GI immunity.[61] Poor sleep can also result in lower melatonin levels

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Acknowledgements The authors acknowledge financial support from the National Natural Science Foundation of China (Grant No