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The results showed that the formulation was well-tolerated, with no significant changes noted in tear film break-up time (TBUT), ocular surface staining, or ocular surface disease index (OSDI) ratings between the two regimens and associated with improvements in patients with moderate DED [100]

Pharmacol, Biochem Behav 104:10512 Forester BP, Zuo CS, Ravichandran C, Harper DG, Du F, Kim S, Cohen BM, Renshaw PF (2012) Coenzyme Q10 effects on creatine kinase activity and mood in geriatric bipolar depression