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Although ideal production of melanin is associated with an effective defense against UV radiations, abnormal melanin biosynthesis and accumulation have been linked to several dermatological disorders in humans, such as hyperpigmentation and skin cancer

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CAH-X chimera 3 (CH-3) has TNXB exons 4144 replaced by TNXA and is characterized by the presence of three TNXA derived missense variants

Hence, we might be able to propose that, the authorities should be cautious about coadministrating the drugs with hepatic enzymeinducing properties, such as phenobarbital, with antithyroid medications

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