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These mediators include the inflammasome complex NOD-like receptor thermal protein domain associated protein 3 (NLRP3), and tumor necrosis factor-alpha (TNF-), which in turn exacerbate the dendritic and synaptic impairments leading to neuronal death and promote AD progression [13,14,15]

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Myo-inositol is best known for its role in PCOS, but a smaller body of research has looked at it in non-PCOS women undergoing IVF