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These factors collectively drive the progressive damage of biliary epithelial cells by autoantibodies, leading to cholestasis, fibrosis, and potential progression to cirrhosis or liver failure (217)

This could be potentially due to instability of GSH under these conditions

Selenium content of the soil can indirectly affect the meat content of selenium through the amount of selenium in the plants that animals eat

Good hygiene prevents contamination that could cause infection or peptide degradation