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Electron microscopy was not applied in the study due to the long post-mortem period

The identification of reliable validated biomarkers could facilitate earlier and more accurate diagnosis and drive the development of targeted pharmacological therapies that might address the underlying pathophysiology of these diseases

However, it can absolutely create a cascade of side effects that indirectly lead to weight loss for some individuals

The studies are categorized as animal studies and human studies, as shown in the table below

The homocysteine-lowering effect of folic acid may play a critical role in reducing the risk of NTD (58, 59)