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Enzyme Inhibitors Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction

Bach Journal: Endocrinology Journal ranking: Q1 Key takeaways: Prolactin stimulates thymic hormone production and cell proliferation in both human and mouse thymic epithelial cells, indicating a direct role of the pituitary gland in thymic hormone regulation

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This study demonstrated that different analogs have variable abilities to bind HGF, and that the analogs showing antagonism to HGF are acting as a Hinge mimics D-Nle-X-Ile-NH(CH 2 ) 5 CONH 2 derivatives were found to compete with Hinge for HGF binding and exhibited a range of affinities for HGF, with K i s ranging from 1.3710 7 -1.3310 10 M ( 26 , 27 )