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In erythrocytes, GSH-Px is the most effective antioxidant against oxidant stress and has some important functions in phagocytic cells [34]: GPx is an enzyme responsible for the removal of hydroperoxides formed in cells

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J Annu Rev Med 57:118 Senger DR, Davis GE (2011) Angiogenesis

while excessively high levels of ROS causing lipid, protein and DNA cell damage are known as oxidative stress (Schieber and Chandel, 2014)

However, our study suggests that FUT2, through its regulation of the cross-talk between gut microbes and the human host, might explain a part of the observational association between serum vitamin B12 and BMI