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Dose ranges come from allometric scaling (using a math formula to translate a mouse mg/kg dose into a human dose) and from research community use

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Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms

For individuals with digestive sensitivities, those taking acid-reflux medications, or anyone on a plant-based (vegan/vegetarian) diet, absorbing enough B12 through food or pills is virtually impossible

Vitamin B12 shots can often undo symptoms of a low vitamin B12 level but the issue is that you might not have any idea that your B12 levels are low to begin with