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Researchers planning translational work should include pharmacokinetic studies with plasma concentration measurements before designing efficacy protocols

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With intramuscular administration, creatinine levels may increase, this should be considered when making a diagnosis

Cellular copper homeostasis is tightly regulated by copper-dependent proteins such as copper transporter 1 (CTR1) for uptake, copper chaperones for transport, and copper-transporting P-type ATPases (copper ATPases) for export, ensuring that optimal intracellular copper levels are crucial for overall health

In some countries neonatal screening programs are established as part of the strategy for prevention of severe neonatal jaundice