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This work lays a solid foundation for the development of sequential therapeutic agents that target vascular repair and provides robust scientific evidence to optimize strategies for the prevention and treatment of tissue injury across various contexts

While activation of IGF1R during aging results in poorer cardiac function and shortened lifespan

Simani L, Ramezani M, Darazam IA, Sagharichi M, Aalipour MA, Ghorbani F, et al

The Nutrigenomic Link to Endogenous Antioxidants Nutrigenomically active phytochemicals exhibit a number of different mechanisms as modulators of the expression of genes coding for enzymes which are active in diverse pathways [62]

Rodent models consistently demonstrate that bone-marrow, adipose, umbilical-cord, placental and menstrual-blood MSCs can restore oestrous cycling, replenish multi-stage follicle pools and even support live births after exposure to alkylating agents, platinum compounds or radiation