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There was no effect of L-carnitine on other serum lipids (i.e., total and HDL-cholesterol, triglycerides) and anemia-related indicators (i.e., hemoglobin concentration, hematocrit, albumin, and required dose of recombinant erythropoietin) (73)

The loss of one allele of Kat6a causes isolated cardiac septum defects with 10% penetrance (Voss et al, 2012)

doi: 10.1016/j.intimp.2025.114446 277 YinLBingZZhengYPanYDongYWangJet al

At the same time, rigorous clinical trials must be designed and conducted to verify the therapys efficacy and safety, providing high-level evidence for subsequent clinical application