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Additional studies using the ASBT inhibitor volixibat in LDLr leiden knockout mice supported that conclusion and demonstrated a significant decrease in diet-induced Non-alcoholic fatty liver disease activity score by the inhibition of ASBT (55)

Allocation of arms (start, other, and novel) to specific spatial locations was counterbalanced within each experimental group

In short, the gut microbiota influences brain function via the regulation of neurotransmitters and neurotrophic factors, maintenance of intestinal barrier and tight junction integrity, activation of enteric sensory afferents, production of bacterial metabolites, and modulation of mucosal immune responses [22]

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