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Human breast carcinoma (MCF-7) cells were procured from NCCS, Pune, India

PMID 17434786

Neurological symptoms often develop gradually and may include: Paraesthesia : tingling or 'pins and needles' sensations, typically starting in the feet and hands Numbness : reduced sensation in the extremities, which may affect balance and coordination Burning pain : particularly in the feet, often worse at night Weakness : muscle weakness and difficulty walking Balance problems : unsteady gait and increased fall risk due to proprioceptive impairment Cognitive changes : memory problems, confusion, difficulty concentrating, and mood disturbances Haematological signs may accompany neurological symptoms and include fatigue, weakness, pallor, and shortness of breath due to megaloblastic anaemia

conversely, an aggravated course of ischemic colitis was observed in L-NAME-treated rats, L-arginine-treated rats, and in IC rats (Tables 1-3 and Figures 1-25)

For instance, both A and Tau can both be bound by ApoE (Chen et al., 2017