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Human studies have produced mixed results, but longer-term research suggests that ordinary oral glutathione can increase glutathione stores in some blood and tissue compartments

Laboratory experiments have revealed that AS-IV reduces GSH levels, alters the size and structure of mitochondria in RPE cells, enhances cellular antioxidant capabilities to mitigate ferroptosis, and ultimately decreases high glucose-induced RPE cell death through the miR-138-5p/SIRT1/NFE2L2 pathway (Tang et al., 2022)

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When GSH is depleted or when oxidised GSSG accumulates, cells experience damage that accelerates ageing, inflammation, and chronic disease

Due to the disruption that pro inflammatory grains, sugar and alcohol have on the delicate balance of the micro flora in the digestive system