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Sources: Pickart & Margolina, Int J Mol Sci 2018 (PMID: 29986520) | Pickart et al., BioMed Res Int 2015 (PMID: 26236449) Security Profile & Chemical Identity Molecular specifications and documented tolerance in clinical studies GHK-Cu Chemical Identity Natural copper complex of the tripeptide glycyl-L-histidyl-L-lysine GHK-Cu Tolerance & Status Safety data from clinical and cosmetic studies Published Clinical & Preclinical Data Key studies published in Int J Mol Sci, BioMed Res Int and dermatological journals -55.8% Reduction in wrinkle volume after 12 weeks of topical application of GHK-Cu cream Anti-Aging Results (12 weeks) 4 000+ Human genes modulated by GHK-Cu (31.2% of the genome) Genomic Impact + 70 % Increased collagen synthesis in human skin fibroblasts Collagen Stimulation Comparison Published Clinical & Preclinical Data Key studies published in Int J Mol Sci, BioMed Res Int and dermatological journals -55.8% Reduction in wrinkle volume after 12 weeks of topical application of GHK-Cu cream Anti-Aging Results (12 weeks) 4 000+ Human genes modulated by GHK-Cu (31.2% of the genome) Genomic Impact + 70 % Increased collagen synthesis in human skin fibroblasts Collagen Stimulation Comparison Important Notice Search Only Not intended for human consumption

A global measure of perceived stress

Marker intensity threshold was set to 2000 cps, mass window was 0.02 Da, retention time window was 0.1 s and data were de-isotoped

A seminal cross-species analysis by Gaylord et al