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Heres what Midis team of medical experts currently recommend: If you generally want to improve gut health: Make sure you have foundational gut-health habits in check, like getting plenty of fiber and staying hydrated
Pharmacokinetics: Cyanocobalamin is administered intranasally, orally, and parenterally, while hydroxocobalamin is administered only parenterally. Once absorbed, vitamin B12 is highly bound to transcobalamin II, a specific B-globulin carrier protein and is distributed and stored primarily in the liver as coenzyme B12. The bone marrow also stores a significant amount of the absorbed vitamin B12. This vitamin crosses the placenta and is distributed into breast milk. Enterohepatic recirculation conserves systemic stores. The half-life is about 6 days (400 days in the liver). Elimination is primarily through the bile; however, excess cyanocobalamin is excreted unchanged in the urine
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Longer-term use may be required for nerve recovery or more complex injuries
The standard reconstitution protocol uses 2mL bacteriostatic water per 50mg vial, yielding 25mg/mL concentration, but some researchers use 1mL to create 50mg/mL solutions for smaller injection volumes
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