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Warmth without visible erythema or swelling occurs in approximately 810% of patients and typically reflects subcutaneous inflammatory mediator release rather than infection

A haplotype in the 5-upstream region of the NDUFV2 gene is associated with major depressive disorder in Han Chinese

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Amyloidogenic proteins then interact with cardiolipin in the outer membrane to induce an apoptotic cascade, resulting in neuronal cell death and, ultimately, neurodegenerative disease