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B12 deficiency can slow down the metabolic rate and lead to fatigue

Anticancer Res 37:53735381 Ghosh P, Roy SS, Basu A, Bhattacharjee A, Bhattacharya S (2015) Sensitization of cisplatin therapy by a naphthalimide based organoselenium compound through modulation of antioxidant enzymes and p53 mediated apoptosis

3 Repetition time

Oncogene 27 (32), 45034508

Identify gaps in the literature and ongoing research directions Key gaps include a lack of large, controlled clinical trials, unclear optimal dosing and delivery for reproductive targets, limited long-term safety data for systemic use, and few mechanistic human studies linking molecular changes to fertility outcomes