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In particular, it highlights the role of the thiomethyl shunt pathway to form thiomethyl metabolites that could be used in the future for a better typing of patients related to the kinetic elimination of APAP and to assess inter-individual susceptibility to APAP-induced hepatotoxicity
Grahn, E., Novotny, M., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Madsen, D., Wahlberg, M., Mannervik, B., Kleywegt, G.J
Glass DA 2nd, Karsenty G