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The authors described fewer daytime sleep attacks and changes in alertness, performance and night-time sleep organisation

Intramuscular injection has its placeprimarily for larger volume injections, oil-based compounds, or specific protocolsbut it shouldn't be the default choice for peptide administration

They act on different appetite pathways cagrilintide is a long-acting amylin analog, while tirzepatide is a dual GIP/GLP-1 receptor agonist which is the theoretical reason researchers discuss pairing them

Instead, its effects on wakefulness appear to be a downstream consequence of its interaction with major neurotransmitter systems

PMCID: PMC6271067.